HPLC Columns
Waters Corp Atlantis HILIC Column, Silica, 3 μm, 100 Å, 4.6 × 50 mm
Atlantis HILIC Silica columns efficiently separate very polar compounds not retained by reverse-phase chromatography. They utilize high organic mobile phases and Hydrophilic Interaction Chromatography (HILIC) for orthogonal selectivity. These columns enhance LC/ESI-MS response and are compatible with SPE solvents, leading to higher sensitivity.
- Exceptional retention of very polar compounds.
- Improved LC/ESI-MS response.
- Direct compatibility with SPE solvents, enhancing sensitivity and lowering detection limits.
- Complementary selectivity to reversed-phase HPLC columns for challenging basic polar analytes.
- Long column lifetime.
- Outstanding column-to-column reproducibility.
Mac-Mod Vydac Denali C18, 120 Å, 15 µm, 4.6 x 250 mm HPLC Column
Vydac TP was the first range of wide pore media phases developed and became the industry standard for peptide and protein separations. The 300 ¿TP silica gives polypeptide molecules complete access to the interior of the silica pores. Vydac TP is known for long column lifetime and negligible phase leaching. Vydac TP provides reliable protein purifications, scalable from analytical to preparative scale. Vydac 218TP and 238TP are used for small polypeptides of 4-5kDa, enzymatic digest fragments, natural and synthetic peptides and multi-ring compounds. Vydac 208TP is recommended for polypeptides of molecular weight 10-20kDa. Vydac 214TP is recommended for the analysis of glycoproteins, hemoglobin variants, histones, insulin variants and membrane proteins. Vydac 219TP is suitable for polypeptides with aromatic side chains, large hydrophobic proteins, membrane-spanning peptides, lipid peptides and fusion proteins from inclusion bodies.
Mac-Mod Evosphere C12, 100 Å, 5 µm, 0.075 x 150 mm Monodisperse Fully Porous Particle HPLC Column
Evosphere UHPLC and HPLC columns are 100 A Monodispersed Fully Porous Silica-based columns designed to combine the benefits of Fully Porous and Core-Shell particle technology into an improved particle design and morphology that brings cutting-edge loading capacity to ultra-high-resolution particle columns. The Monodispersed Particles provide similar efficiency to Core-Shell products when comparing them directly via particle size matching and significantly increase loadability which allows ultra-high resolution analytical separations to scale to preparative separations for isolation work if needed. The bonded phase chemistries are exciting as well to maximize selectivity with novel C12 bonded phase, 2 multi-modal C18/AR, and C18/PFP bonded phases, an extended and stabilized phenyl funtionality in the Diphenyl bonded phase, a polar endcapped AQUA phase, a Phenyl-Hexyl phase, a propyl PFP phase and the RP18-Amide bonded phases which is great for doing bases at low pH.